I think it might work at Chelsea, where Abramovich takes a strong and active hand. I'm sure he'll review the dynamic between Hiddink and Villas-Boas and just axe whoever he deems necessary if there's a problem.
I still think the players are a bigger source of off-field problems myself. Terry, Lampard, Drogba, Anelka, Cole - talent aside, these aren't guys I'd want to have to take on as a new manager, and they're all slowing down as well.