Qwiss I think he'll want to make a point against City and keep momentum and belief
That could go the other way though. Go all out, lose to their changed line-up and suddenly everyone is asking questions. On the other hand playing a mixed side gives you that little bit of protection against that.
If we want to make changes with minimal impact on style of play then something like this could work.
White - Saliba - Gabriel - Tomi
Vieira - Partey - Xhaka
ESR - Eddie - Trossard
Alternatively if we play one of Saka/Martinelli then I wouldn't mind seeing ESR in the 8 role either.