Their midfield diamond or 442 rhombus or whatever you want to call it works so well. Higuain plays on the last shoulder, Aguero can go up to partner or drop deep or go wide, Messi gets more space than he does when playing for Barca. Di Maria plays both CM and LW at the same time. They've also played 442 with Messi off of a #9.
Not sure if they have enough talent at the back but if Messi, Aguero, and Di Maria are in good physical condition I can see them making the Semi Finals at least.
