I would rotate, the more I look at the squad...the more I'm ok with it, our "back-up" players are very good and we should not be scared to use them against most teams. Olympiakos at home is that sort of game. Not a full rotation, but some players.
Hincapié is still out so that's a shame.
Raya; White, Saliba, Mosquera, MLS; Zubi, Rice, Nwaneri; Martinelli, Eze; Gyokeres
With Madueke out we should play Martinelli there, Saka it's clear that he is not 100% fit yet and we should not push him, that being said, he will play.
I would like to rest and protect Goykeres as well...but he also needs to score, it's been a few games now and here we should score a few, if he gets one fast sub him at HT for Merino, if not at around 60.
Norgaard should also sub Rice around the hour mark.
Rest one of Saliba/Gabriel, and both full backs, they played a lot, and they are injury prone, the back ups are great players.