My sense is that there is still a much larger number of people being murdered in the world than the number becoming the subject of high profile internet pile-ons.
Disgusting as Gamergate is, we wouldn't want to get into a position where we are more concerned about Brianna Wu being dogpiled, doxxed and threatened than by the over 10,000 Americans who actually get murdered year by year.
But switching from the particular to the general, we should probably be very concerned by what the attacks on prominent feminists imply about aggregate hostility to women's empowerment.
Beyond that, there must be a lot of medium profile shenanigans on the internet that escape notice. But then there are lots of sackings, unjust planning decisions, medical scandals, and other major life reversals going on in a fairly arbitrary way all the time.
The question about what kinds of violence are legitimised by the target and the politics is an interesting one, leading straight into idealist versus historicist, dialectic reasoning. Despite our natural distaste for violence, the threat of forceful insurrection has been the foundation of very many of the positive social changes that have transformed our societies.
