There's going to be a lot of rotation this season - as Arsenal fans we've never seen anything like it before purely because we've never had this kind of depth.
Instead of viewing players by their relatively strengths and weaknesses, we almost want to think of them as tools to be used based on the opposition (with the exception of Saka, Odegaard and Saliba).
In this case - teams that are likely to attack us aggressively? Timber probably starts because he's press resistant and can defend. Otherwise Zinchenko for games when we're on the front foot and need to pick a pass through 10 players.