I probably wouldn't play Sterling as anything but a panic sub, and I'd be tempted to play Dier instead of Cahill at CB, if not for the potential lack of understanding.
-----------------Hart
Clyne----Dier-----Smalling--Bertrand
--------------Henderson
---Wilshere--------------Lallana
------------------Alli
----------Vardy----Sturridge
Those Spurs fullbacks are overrated, though Clyne isn't much better. Walker is just too awful and I can't stand Rose.
The 2 CM positions next to Wilshere behind Alli are a bit of a toss up between Henderson, Lallana, Rooney, Milner, Delph, Dier, and Drinkwater, depending upon who actually goes. Not sure how much better or worse any of them would be in there, other than Lallana being the best attacking option.
Rashford and Kane as your main impact subs.